Ovarian cancer youngest age, CURS 3. Invazia locala si metastazarea.pptx
Conținutul
A rapid response is mounted by a front line composed of innate immune cells such as neutrophils, macrophages, mast cells, dendritic cells, eosinophils, and natural killer NK cells. The purpose is to restore homeostasis through several phases: inflammation, tissue formation, and tissue remodeling.
Tumor-associated macrophages TAMs can comprise a large proportion of tumor bulk. Clinical evidence also is pointing toward innate immune cells in cancer progression.
Factorii care indic potenialul metastatic al unei tumori Gradul de invazie a ganglionilor limfatici N. Mrimea tumorii. Fenomenul de metastazare transform cancerul dintr-o boal de organ ntr- una sistemic.
Mutaiile genetice, micromediul tumoral i interaciunile cu celulele gazdei dirijeaz diseminarea metastatic a celulelor tumorale. Procesul de metastazare este un proces complex, selective i ineficient care poate fi mprit n patru etape: invazia, intravazarea, supravieuirea n circulaie i extravazarea. Colonizarea celulelor tumorale necesit capacitatea de a prolifera n esuturi strine i angiogeneza.
Creterea metastazelor reprezint etapa final a numeroase evenimente letale n urma crora supravieuiesc un numr redus de celule.
Ovarian cancer youngest age unei nie premetastatice este esenial pentru creterea celulelor maligne extravazate.
Ovarian Cancer
Specificitatea metastazelor de organ este determinat att de fluxul sangvin ct i de factorii specifici de ovarian cancer youngest age. Tumorile primare prezint celule stem care recapituleaz formarea tumorilor dintr-o singur celul, celule care prezint expresia modificrilor genetice cu creterea potenialului metastatic.
Terapiile sistemice antiimetastatic vor trebui s anihileze numeroase ci biologice care controleaz proliferaraea, invazia i angiogeneza.
Prevenia cancerelor Primary prevention aims to reduce the incidence of cancer by: controlling avoiding exposure to risk factors increasing an individuals resistance to risk factors by immunisation or chemoprevention.
