Papillary thyroid cancer variants
[Differentiated thyroid cancer--peculiar morphological and clinical forms].
Abstract Aim: to describe two cases of familial papillary thyroid carcinoma. Material and methods: patients were investigated by fine needle biopsy, MRI imaging and tumor biopsy, first case and histological examination of colonic and thyroid tumors first case and histological examination of thyroid tumor second case.
Results and discussion: case presentation: first case, 68 years old man had a colonic polyposis attenuated form with only a few polyps and a thyroid nodule.
After hemicolectomy for a supposed colonic carcinoma with liver and lung papillary thyroid cancer variants, histological examination revealed no malignant colonic disease. Two month later the diagnosis of invasive thyroid tumor with lymph node metastases was made, but only an open biopsy was papillary thyroid cancer variants because tumor invasiveness demonstrated on MTI imaging.
The biopsy identified a papillary thyroid carcinoma. Case 2: the son of the patient 30 years old without known diseases was invited to be assessed for thyroid disease.
Ultrasound examination discovered a large nodule with microcalcifications. Microscopic examination done after total thyroidectomy revealed a cribriform morular variant of papillary thyroid carcinoma, a variant that is known to be associated with FAP. Radioiodine ablation was made followed by suppressive thyroxine treatment. In the second case adenomatous polyposis was not found yet. In our knowledge these are the first cases of familial thyroid papillary carcinomas in que es verrugas papiloma setting.
Traducerea «papillary» în 25 de limbi
Familial history allowed an earlier diagnosis and a good management of the disease in the second case. Conclusions: according to the literature and our first experience, screening for thyroid cancer must be done in all patients with FAP and in those with a FAP proband in the family.
Nicolau Institute of Virology, Bucharest, Romania. Introduction: In human cancer cells DNMTs are responsible for both de novo and maintenance methylation of tumor suppressor genes.
Nosé V. Endocr Pathol. Modern Pathology ; SS Cavaco BM.
Endocrine-Related Cancer ; Richards ML. Thyroid ; Nilbert M, Kristoffersson U, Ericsson M, et al: Broad phenotypic spectrum in familial adenomatous polyposis; from early onset and severe phenotypes to late onset of attenuated polyposis with the first manifestation at age BMC Med Genet.
Orphanet J Rare Dis ; 7.
Histopathology ; Asian J Surg. Clin Gastroenterol Hepatol. Clin Colorectal Cancer ; 11 4 : Head Neck ; Ann Surg. Kameyama K, Takami H.
Sinonimele și antonimele papillary în dicționarul de sinonime Engleză
Fam Cancer. Lee S, Hong SW, Shin SJ,et al: Papillary thyroid carcinoma associated with familial adenomatous polyposis: molecular analysis of pathogenesis in a family and review of the literature. Endocr J. Papillary thyroid cancer variants J Otolaryngol.
Cetta F. Acta Cytol. Kurihara K, Shimizu S, Chong J, et al: Nuclear localization of immunoreactive beta-catenin is specific to familial adenomatous polyposis in papillary thyroid carcinoma.
Jpn J Cancer Res. Ito Y, Miyauchi A, Ishikawa H, et al: Our experience of treatment of cribriform morular variant of papillary thyroid carcinoma; difference in clinicopathological features of FAP-associated and sporadic patients.
Mc Donald TJ.
- Intraductal papilloma high risk lesion
Пока экспресс-тротуар выносил их за пределы заполоненного людьми центра города, Алистра -- что было для нее как-то необычно -- не задавала никаких вопросов.
- [Differentiated thyroid cancer--staging and prognostic systems].
- PAPILLARY - Definiția și sinonimele papillary în dicționarul Engleză
Journal of Oncology. Nasr MR. Modern Pathology. Capezzone M.