Hpv 16 breast cancer

Rezumat: Heterogenicitatea celulara prezenta in majoritatea tumorilor reprezinta o provocare pentru terapia antitumorala, deoarece strategiile terapeutice curente tintesc numai celulele care prolifereaza rapid din cadrul tumorii, nereusind hpv 16 breast cancer distruga celule stem tumorale, care sunt mai rezistente la actiunea agentilor chimioterapeutici standard si au abilitatea de a regenera tumora.

The mortality of cervical cancer in Romania is the most important among European countries. The pri­­ma­­ry cause of cervical cancer is a persistent hpv 16 breast cancer by some spe­ci­­fic types of human papillomavirus HPV. Cer­­vi­cal cancer can be prevented by vaccination against HPV infection and scre­ening. Sincemany countries have introduced HPV vac­cines into their national programs. Des­pite the efforts made, the vac­cine coverage is low, and the difficulties encountered are re­la­ted to concerns about vac­­cine safety.

A devenit astfel tot mai evident ca este necesar sa se dezvolte strategii adresate tintit mecanismelor de supravietuire si regenerare hpv 16 breast cancer celulelor stem tumorale. Avand in hpv 16 breast cancer posibilitatea de a identifica si izola CSTG, precum si experienta laboratorului nostru in domeniul celulelor stem si a terapiei antitumorale, ne propunem drept scop utilizarea tehnologiei siRNA pentru a inhiba specific anumite gene supraexprimate in cancerul gastric care prin efectul lor pot fi promotori ai unor procese precum: proliferarea celulara, interactia hpv 16 breast cancer matrixul, motilitate, metastazare, angiogeneza.

Prospective identification of tumorigenic breast cancer cells. Bonnet D, Dick J Hpv 16 breast cancer.

Tinte moleculare

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med ; Chen T, Deng C. Int Immunopharmacol. Unlocking the potential of the human genome with RNA interference.

• Неужели, раздумывал Олвин, любовь и была тем, чего ему всегда не хватало в Диаспаре, и ее-то на самом деле он и стремился найти.

• Madalin Margan - Google Scholar Citations

Nature ; —8 Houghton J, Stoicov C, et al. Gastric cancer originating from bone marrow-derived cells. Science ; — Quante M, Wang TC.

Prevenţia cancerului cervical prin vaccinare în 2019

Inflammation and stem cells in gastrointestinal carcinogenesis, Physiology, ; — Lei XY, Zhong M, et al. Acta Biochim Biophys Sin. Li C, Heidt D G, et al.

Identification of pancreatic cancer stem cells.

Cancer Res ; Prospects of RNA interference therapy for cancer. Global cancer statistics, CA Cancer J Clin. Identification of a cancer stem cell in human brain tumors.

(P) Pentru sănătatea ta – Time To End Breast Cancer

Singh S K, Hawkins C, et al. Identification of human brain tumour initiating cells. Nature ; Takaishi S, Okumura T, et al. Identification of gastric cancer stem cells using the cell surface marker CD Stem Cells. Valean S, Armean P,  et al.

Cancer Mortality in Romania, J Gastrointestin Liver Dis. Zhu H, Mitsuhashi N, et al. The role of the hyaluronan receptor CD44 in mesenchymal stem cell migration in the extracellular matrix. Wang Q, Huang Y, et al.

Cervical cancer prevention through vaccination in 2019

J Biomed Sci. Obiectivele proiectului: 1. Identificarea, izolarea si caracterizarea CSTG. Testarea capacitatii tumorale pe modele animale imunodeficiente.

HPV: Preventing Cervical Cancer

Identificarea unor tinte moleculare prin testarea expresiei genice la nivelul CSTG, si selectarea genelor semnificativ modificate. Inhibarea specifica a expresiei genelor selectate cu ajutorul metodologiei siRNA 4.

Analiza efectelor induse de terapia moleculara asupra functionalitatii CSTG. Plan de realizare: Etapa I 12 august — 10 decembrie Obiectiv: Identificarea, izolarea si caracterizarea celulelor stem tumorale gastrice in linii celulare si culturi primare de adenocarcinom gastric.

Citations per year

Buget: Studiu de evaluare a performantelor metodei de selectie propuse. Elaborarea unui articol stiintific acceptat spre publicare intr-o revista ISI Hepato-Gastroenterology, programat pentru numarul Etapa II 10 decembrie — 10 decembrie Obiectiv 1: Testarea capacitatii tumorigeneza pe modele animale imunodeficiente. Obiectiv 2: Identificarea unor tinte moleculare prin testarea expresiei genice la nivelul celulelor stem tumorale gastrice, si selectarea genelor semnificativ modificate.