NEUROLOGICAL MANIFESTATIONS IN SPORADIC EUTHYROID GOITER

Intraductal papilloma frequency, NEUROLOGICAL MANIFESTATIONS IN SPORADIC EUTHYROID GOITER - SNPCAR

Clinical endocrinological diagnosis was established based on the thyromegaly and euthyroid status.

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Neuropsychiatric manifestations seen in patients with goiter from the study group included: 1. Psychiatric accuses: 63 cases — Intraductal papilloma frequency disorders encountered in the study group included somatization disorders with dissociative symptoms, somatoform disorders, conversive disorders, anxiety and depression syndromes, relatively common in patients with euthyroid goiter.

Left transient paresthesia syndromes were common and of functional nature: — Conversive disorders — 4 cases — 2. Headaches: 52 cases — Vertigo — 38 cases — Fainting — 6 cases — 3.

Tremor — 6 cases — 3.

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Muscular cramps — 2 cases — 1. Osteotendinous hyperrelfexia — 2 cases — 1.

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Essential trigeminal neuralgia — 1 case — 0. Clinically confirmed sensory neuropathy with disorders of superficial and profound sensory disorders in the lower limbs — 2 cases intraductal papilloma frequency 1. Stroke — intraductal papilloma frequency cases The prevalence of stroke in patients with euthyroid goiter from the study group. Neurofibromatosis — 1 case — 0.

NEUROLOGICAL MANIFESTATIONS IN SPORADIC EUTHYROID GOITER

Ocular myasthenia gravis — 2 cases intraductal papilloma frequency 1. Euthryoid goiter associated with multiple sclerosis, remitting — recurrent form — 1 case — 0. Associations between euthyroid goiter, intraductal papilloma frequency gravis, rheumatoid arthritis, systemic vasculitis with secondary neuropathy — 1 case — 0.

The diagnosis was clinically and paraclinically confirmed through mediastinum radiography, mediastinum CT, intraductal papilloma frequency scintigram. From the patients, 4 have undergone surgery followed by substitution with thyroid hormone treatment in the recurrent case the patient refused another intervention.

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On the subsequent checks that occurred every 3 months the evolution was favorable in all 4 cases, the initial signs and symptoms disappearing completely. Patient S.

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Personal history: unimportant. Clinical exam: lowering of the soft palate on the right side; thyromegaly grade II.

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  • NEUROLOGICAL MANIFESTATIONS IN SPORADIC EUTHYROID GOITER - SNPCAR

Laboratory exam: T3 — Thyroid ultrasound: both thyroid lobes were increased in size, homogeneous structure. Thyroid scintigraphy fig 6 : Fig 6. Thyroid scinitgraphy — patient M.

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Thoracic mediastinum CT fig. Intraductal papilloma frequency are no encountered mediastinum adenopathies nor in the pulmonary hilum. E, fig.

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Anizofollicular aspect, epithelial hyperactivity is highlighted, with maximum use of the colloid; The follicles have different sizes, some of them being cystic dilated; thyroid vesicles are much wider and thyroid cells are flattened, the colloid is homogeneous, intensely colored.

Paraclinically the endocrinological diagnosis of sporadic euthyroid goiter was established by: — Hormonal dosages; — Thyroid ultrasound fig.

Isthmus has a size of 7mm. The right thyroid lobe is occupied by nodular structures, the biggest one being located median, with a diameter of 14 mm. Parazitii londra 3 noiembrie capture on the projection area of theright thyroid lobe. Inhomogeneous capture in both lobes, sketching a hypocaptation area in the left lobe, in the inferior — exterior side, and the small area of hypocaptation in the lower pole of the right lobe.

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These investigations have been exemplified above. The paraclinical neurological diagnosis included: — FO exam; — Electromyographic examination; — Neuroimaging CT examination; In the study group we encountered associations of signs of hyperprolactinemia galactorrheawith elevated values of PRL prolactin — Brain CT disconfirmed the diagnosis.

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In 6 of the cases with persisting vertigo and balance disorders without response to treatment, a brain CT was carried out which detected a diffuse cerebral and cerebellar atrophy. Cases of training headache associated with vertigo and thyromegaly have been evaluated through brain CT without detecting any changes in the brain.

Also, brain CT was performed for sensory syndromes in a intraductal papilloma frequency with prolonged evolution, detecting only cortical atrophy. Neuroimaging evaluation was imposed for the association of thyro-ovarian failure with training headache, galactorrhea and fainting, with a suspicion of pituitary adenoma, but it had not been confirmed by the brain CT.

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In intraductal papilloma frequency case with normal prolactin levels, headache, goiter and galactorrhea the diagnosis in the end was of intraductal breast papilloma. For cases with myasthenia gravis and plunging intrathoracic goiter, we performed mediastinum CT.

Also, CT examination was performed in cases of stroke and in cases which required the study of the orbit and exophthalmometry. Euthyroid goiter was not associated with any specific neurological symptoms, the changes being predominantly subjective, the psychiatric accuses being more predominant.

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The persistence of some subjective accuses such as vertigo and headache have required neuroimaging investigations. In cases with bulky goiter or endothoracic goiter we encountered compression phenomena of the mediasinum structures or of the cervical neurovascular package.

In some situations we have registered cases of diplopia with unclear etiology, without it belonging to a neurological cause or an endocrinological one because we could not establish it with certainty.

We call that diplopia may precede with a few years the installation of thyroid disorders. We were not able to establish a direct cause or link between the two conditions, we have encountered associations intraductal papilloma frequency euthyroid goiter and myasthenia gravis, multiple sclerosis, neurofibromatosis and stroke.